Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.49 |
| ▸ | GLS | O94925 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332307 | 0.79 | DCTPP1 (0.49) | DCTPP1LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL7897455 | 0.73 | DCTPP1 (0.46) | DCTPP1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL7332530 | 0.71 | DCTPP1 (0.41) | DCTPP1KDM4EALDH1A1SMN1; SMN2IDO1 | |
| SCHEMBL7327647 | 0.70 | MAPT (0.44) | DCTPP1LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL7338080 | 0.69 | DCTPP1 (0.42) | DCTPP1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7339898 | 0.68 | ALDH1A1 (0.55) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL7339811 | 0.65 | DCTPP1 (0.43) | DCTPP1LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL26820508 | 0.64 | KMT2A (0.58) | LMNAMAPTALDH1A1GAACYP3A4 | |
| SCHEMBL29110675 | 0.64 | KMT2A (0.58) | LMNAMAPTALDH1A1GAACYP3A4 | |
| SCHEMBL7050949 | 0.64 | TSHR (0.59) | LMNAKDM4EMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191124-B1 | VIRICIDES | PHARMACIA & UPJOHN COMPANY | 2001-02-20 | — | — | US | disclosed |
| EP-0757692-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029922-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-09 | — | — | WO | disclosed |