Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 15/20 | 0.54 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CTSE | P14091 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709619 | 0.92 | CTSS (0.53) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL7272375 | 0.92 | CTSS (0.53) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL13306504 | 0.92 | CTSS (0.53) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL7297295 | 0.91 | CTSS (0.52) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL27625588 | 0.91 | CTSS (0.51) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL9848334 | 0.91 | CTSS (0.56) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL6448979 | 0.91 | CTSS (0.56) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL8536013 | 0.91 | CTSS (0.56) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL7284721 | 0.89 | CTSS (0.55) | RENCTSSCTSKCTSDCTSE | |
| SCHEMBL7265165 | 0.89 | CTSS (0.50) | RENCTSSCTSKCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410278-B1 | Renin inhibiting aminooligohydroxy-derivatives | HOECHST AG (DE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0410278-A1 | Renin inhibiting aminooligohydroxy-derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-30 | — | — | EP | disclosed |