Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | REN | P00797 | 11/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | CTSE | P14091 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448979 | 1.00 | CTSS (0.56) | CTSSCTSKRENCA1CA2 | |
| SCHEMBL8536013 | 1.00 | CTSS (0.56) | CTSSCTSKRENCA1CA2 | |
| SCHEMBL7265417 | 0.95 | CTSS (0.52) | CTSSCTSKRENCA1CA2 | |
| SCHEMBL7272524 | 0.93 | CTSS (0.51) | CTSSCTSKRENCA1CA2 | |
| SCHEMBL7272530 | 0.93 | CTSS (0.51) | CTSSCTSKRENCA1CA2 | |
| SCHEMBL5709574 | 0.93 | CTSS (0.53) | CTSSCTSKRENCA1CA2 | |
| SCHEMBL7284721 | 0.93 | CTSS (0.55) | CTSSCTSKRENCA1CA2 | |
| SCHEMBL7297295 | 0.92 | CTSS (0.52) | CTSSCTSKRENCA1CA2 | |
| SCHEMBL7339890 | 0.91 | CTSS (0.51) | CTSSCTSKRENCA1CA2 | |
| SCHEMBL7329863 | 0.91 | REN (0.54) | CTSSCTSKRENCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428849-A2 | Retroviral protease inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-29 | — | — | EP | disclosed |