SCHEMBL733004

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3493736	1.00	KMT2A (0.51)	KMT2ARETGPR119HDAC3HDAC4
	SCHEMBL733298	0.86	HDAC3 (0.50)	KMT2AHDAC3HDAC4HDAC1HDAC7
	SCHEMBL741154	0.84	KMT2A (0.49)	KMT2AGPR119
	SCHEMBL730422	0.83	ACACB (0.51)	KMT2AGPR119HDAC3HDAC4HDAC1
	SCHEMBL13522727	0.82	HDAC3 (0.47)	KMT2AHDAC3HDAC4HDAC1HDAC7
	SCHEMBL309037	0.82	GPR119 (0.58)	KMT2AGPR119HDAC3HDAC4HDAC1
	SCHEMBL743378	0.82	ACACB (0.50)	KMT2AGPR119HDAC3HDAC4HDAC1
	SCHEMBL308972	0.81	ACACB (0.51)	KMT2AGPR119HDAC3HDAC4HDAC1
	SCHEMBL21467195	0.81	KMT2A (0.59)	KMT2AGPR119HDAC3HDAC4HDAC1
	SCHEMBL3494576	0.81	KMT2A (0.62)	KMT2AGPR119HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.