Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | MC5R | P33032 | 3/20 | 0.46 |
| ▸ | MC3R | P41968 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325675 | 0.97 | MC4R (0.47) | MC4RSLC6A4MC5RMC3RDRD2 | |
| SCHEMBL7333675 | 0.96 | DRD2 (0.47) | MC4RMC5RMC3RDRD2DRD3 | |
| SCHEMBL7336174 | 0.94 | HTR1A (0.47) | MC4RMC5RMC3RBCHEDRD2 | |
| SCHEMBL7329410 | 0.89 | SLC6A4 (0.50) | MC4RSLC6A4MC5RMC3RBCHE | |
| SCHEMBL7332251 | 0.88 | ALDH1A1 (0.45) | MC4RMC5RMC3RBCHEDRD2 | |
| SCHEMBL7324350 | 0.86 | MC4R (0.48) | MC4RSLC6A4MC5RMC3RBCHE | |
| SCHEMBL7332178 | 0.85 | MC4R (0.47) | MC4RSLC6A4MC5RMC3RBCHE | |
| SCHEMBL7327297 | 0.84 | BCHE (0.48) | MC4RSLC6A4MC5RMC3RBCHE | |
| SCHEMBL7327584 | 0.81 | DRD2 (0.55) | DRD2DRD3 | |
| SCHEMBL7327911 | 0.80 | ALDH1A1 (0.58) | MC4RSLC6A4MC5RMC3RBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402923-A2 | 2,5-Diaminotetralines, process for their preparation and their use as medicine | BOEHRINGER INGELHEIM KG (DE) | 1990-12-19 | — | — | EP | disclosed |