Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.71 |
| ▸ | CTSS | P25774 | 5/20 | 0.71 |
| ▸ | PPARG | P37231 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | REN | P00797 | 3/20 | 0.56 |
| ▸ | KLK7 | P49862 | 2/20 | 0.56 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323154 | 0.98 | PPARA (0.69) | PPARACTSSPPARGRAB9AREN | |
| SCHEMBL24102984 | 0.91 | CTSS (0.68) | PPARACTSSPPARGRAB9AREN | |
| SCHEMBL7324916 | 0.91 | CTSS (0.68) | PPARACTSSPPARGRAB9AREN | |
| SCHEMBL1132901 | 0.88 | PPARA (0.90) | PPARACTSSPPARGRAB9AKLK7 | |
| SCHEMBL828674 | 0.88 | PPARA (0.90) | PPARACTSSPPARGRAB9AKLK7 | |
| SCHEMBL17051 | 0.88 | PPARA (0.90) | PPARACTSSPPARGRAB9AKLK7 | |
| SCHEMBL3683228 | 0.87 | CTSS (0.75) | PPARACTSSPPARGRAB9AREN | |
| SCHEMBL29979082 | 0.87 | PPARA (0.76) | PPARACTSSPPARGRAB9AREN | |
| SCHEMBL27287363 | 0.87 | PPARA (0.54) | PPARACTSSPPARGRAB9AREN | |
| SCHEMBL31107864 | 0.86 | CTSS (0.62) | PPARACTSSPPARGRAB9AREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |