Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.56 |
| ▸ | F2 | P00734 | 13/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336874 | 0.98 | F10 (0.53) | F10F2PRSS1NR4A2TRPM8 | |
| SCHEMBL7332190 | 0.88 | ATM (0.48) | NR4A2TRPM8 | |
| SCHEMBL7331554 | 0.88 | F10 (0.56) | F10F2PRSS1NR4A2 | |
| SCHEMBL7330771 | 0.87 | ATM (0.50) | NR4A2TRPM8 | |
| SCHEMBL7331577 | 0.85 | F10 (0.53) | F10F2PRSS1NR4A2 | |
| SCHEMBL7330613 | 0.84 | F10 (0.52) | F10F2PRSS1 | |
| SCHEMBL7330045 | 0.82 | KMT2A (0.47) | NR4A2 | |
| SCHEMBL7338009 | 0.82 | KMT2A (0.50) | NR4A2TRPM8 | |
| SCHEMBL7329854 | 0.80 | L3MBTL1 (0.62) | NR4A2 | |
| SCHEMBL7336057 | 0.78 | L3MBTL1 (0.51) | NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430047-A | Neurotensin antagonists | WARNER-LAMBERT COMPANY (US) | 1995-07-04 | — | — | US | claimed |
| US-5430047-A | Neurotensin antagonists | WARNER-LAMBERT COMPANY (US) | 1995-07-04 | — | — | US | disclosed |