Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332190 | 0.99 | ATM (0.48) | ATML3MBTL1ANPEPENPEPKMT2A | |
| SCHEMBL7330045 | 0.92 | KMT2A (0.47) | ATMANPEPENPEPKMT2ANR4A2 | |
| SCHEMBL7338009 | 0.92 | KMT2A (0.50) | ATML3MBTL1ANPEPENPEPKMT2A | |
| SCHEMBL7329854 | 0.89 | L3MBTL1 (0.62) | L3MBTL1KMT2ANR4A2MEN1POLB | |
| SCHEMBL7330946 | 0.87 | L3MBTL1 (0.52) | ATML3MBTL1KMT2APOLBHTT | |
| SCHEMBL7330338 | 0.87 | F10 (0.56) | NR4A2TRPM8 | |
| SCHEMBL7336874 | 0.87 | F10 (0.53) | NR4A2POLBTRPM8 | |
| SCHEMBL7336057 | 0.87 | L3MBTL1 (0.51) | ATML3MBTL1KMT2ANR4A2POLB | |
| SCHEMBL7337342 | 0.84 | KMT2A (0.52) | ATML3MBTL1ANPEPENPEPKMT2A | |
| SCHEMBL7332819 | 0.81 | L3MBTL1 (0.50) | L3MBTL1KMT2AMEN1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430047-A | Neurotensin antagonists | WARNER-LAMBERT COMPANY (US) | 1995-07-04 | — | — | US | claimed |
| US-5430047-A | Neurotensin antagonists | WARNER-LAMBERT COMPANY (US) | 1995-07-04 | — | — | US | disclosed |