Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 9/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331554 | 0.96 | F10 (0.56) | F10MEN1KMT2AF2PRSS1 | |
| SCHEMBL7331577 | 0.96 | F10 (0.53) | F10MEN1KMT2AF2PRSS1 | |
| SCHEMBL7337342 | 0.87 | KMT2A (0.52) | MEN1KMT2AMAPTL3MBTL1PDPK1 | |
| SCHEMBL7330338 | 0.84 | F10 (0.56) | F10F2PRSS1 | |
| SCHEMBL7336874 | 0.84 | F10 (0.53) | F10F2PRSS1 | |
| SCHEMBL8087232 | 0.82 | ATM (0.56) | F10F2MAPTL3MBTL1DPP4 | |
| SCHEMBL7330045 | 0.81 | KMT2A (0.47) | MEN1KMT2APDPK1MRGPRX4 | |
| SCHEMBL7328500 | 0.81 | POLB (0.56) | MEN1KMT2AL3MBTL1PDPK1NPC1 | |
| SCHEMBL7328371 | 0.79 | L3MBTL1 (0.62) | MEN1KMT2AL3MBTL1MRGPRX4NPC1 | |
| SCHEMBL7330976 | 0.77 | L3MBTL1 (0.53) | MEN1KMT2AMAPTL3MBTL1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430047-A | Neurotensin antagonists | WARNER-LAMBERT COMPANY (US) | 1995-07-04 | — | — | US | claimed |
| US-5430047-A | Neurotensin antagonists | WARNER-LAMBERT COMPANY (US) | 1995-07-04 | — | — | US | disclosed |