Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326127 | 0.99 | L3MBTL1 (0.54) | L3MBTL1TDP1HDAC8HDAC3HDAC4 | |
| SCHEMBL10725421 | 0.87 | L3MBTL1 (0.59) | L3MBTL1TDP1HDAC8HDAC3HDAC4 | |
| SCHEMBL6789754 | 0.85 | ALDH1A1 (0.57) | L3MBTL1TDP1HDAC8HDAC3HDAC4 | |
| SCHEMBL9329980 | 0.81 | TDP1 (0.52) | L3MBTL1TDP1HDAC8HDAC3HDAC4 | |
| SCHEMBL20023143 | 0.80 | HTT (0.58) | L3MBTL1TDP1HDAC8HDAC3HDAC4 | |
| SCHEMBL607631 | 0.80 | HDAC8 (0.69) | L3MBTL1TDP1HDAC8HDAC3HDAC4 | |
| SCHEMBL3468927 | 0.80 | HDAC8 (0.69) | L3MBTL1TDP1HDAC8HDAC3HDAC4 | |
| SCHEMBL9899475 | 0.80 | HDAC8 (0.69) | L3MBTL1TDP1HDAC8HDAC3HDAC4 | |
| SCHEMBL9350109 | 0.80 | HDAC8 (0.69) | L3MBTL1TDP1HDAC8HDAC3HDAC4 | |
| SCHEMBL4202491 | 0.80 | HDAC8 (0.69) | L3MBTL1TDP1HDAC8HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472380-A | CARBOXYALKYL DIPEPTIDE DERIVATIVES | MERCK & CO., INC. (US) | 1984-09-18 | — | — | US | disclosed |
| US-4374829-A | Aminoacid derivatives as antihypertensives | MERCK & CO., INC. (US) | 1983-02-22 | — | — | US | disclosed |
| EP-0012401-A1 | Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them | MERCK & CO. INC. (US) | 1980-06-25 | — | — | EP | disclosed |