Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | LTA4H | P09960 | 11/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7359209 | 0.95 | LTA4H (0.55) | HRH3LTA4HKDM4EMEN1ALDH1A1 | |
| Oxalic Acid SCHEMBL7359206 | 0.95 | LTA4H (0.55) | HRH3LTA4HKDM4EMEN1ALDH1A1 | |
| SCHEMBL7329491 | 0.84 | MEN1 (0.50) | HRH3LTA4HMEN1ALDH1A1KMT2A | |
| SCHEMBL14139379 | 0.84 | LTA4H (0.52) | HRH3LTA4H | |
| SCHEMBL7322832 | 0.83 | SLC2A1 (0.59) | HRH3LTA4HSLC2A1 | |
| Oxalic Acid SCHEMBL7324624 | 0.82 | HCRTR1 (0.52) | HRH3LTA4HKDM4EMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7321449 | 0.82 | SLC2A1 (0.58) | HRH3LTA4HSLC2A1 | |
| SCHEMBL11447662 | 0.81 | LTA4H (0.53) | HRH3LTA4H | |
| SCHEMBL7327714 | 0.79 | HCRTR1 (0.55) | LTA4HKDM4EALDH1A1S1PR4S1PR1 | |
| SCHEMBL7326161 | 0.79 | LTA4H (0.62) | HRH3LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629190-A1 | COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-12-21 | — | — | EP | claimed |
| WO-1993015052-A1 | COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | claimed |