Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 9/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330935 | 0.83 | ABCB1 (0.39) | ABCB1ABCC9KDM4E | |
| SCHEMBL7325866 | 0.82 | ABCB1 (0.39) | ABCB1ABCC9KDM4E | |
| SCHEMBL7331870 | 0.80 | ABCC9 (0.39) | ABCB1ABCC9KDM4E | |
| SCHEMBL7335897 | 0.80 | ABCB1 (0.59) | ABCB1ABCC9 | |
| SCHEMBL7358720 | 0.78 | ABCC9 (0.41) | ABCB1ABCC9KDM4E | |
| SCHEMBL8541387 | 0.77 | ABCB1 (0.40) | ABCB1ABCC9KDM4E | |
| SCHEMBL8544061 | 0.77 | ABCB1 (0.40) | ABCB1ABCC9KDM4E | |
| SCHEMBL8539388 | 0.77 | ABCB1 (0.40) | ABCB1ABCC9KDM4E | |
| SCHEMBL7325525 | 0.74 | ABCB1 (0.39) | ABCB1ABCC9KDM4E | |
| SCHEMBL9443572 | 0.73 | ABCC9 (0.42) | ABCB1ABCC9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5387587-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |
| EP-0363883-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1990-04-18 | — | — | EP | disclosed |