SCHEMBL7330769

SCHEMBL7330769

CCCC[C@@H](CO)NC(=O)[C@@H](N)CC(C)C

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 11/20 0.45
DPP9 Q86TI2 9/20 0.45
DPP8 Q6V1X1 9/20 0.45
DPP4 P27487 6/20 0.45
SLC15A1 P46059 1/20 0.45
PLA2G10 O15496 2/20 0.40
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39
SLC7A5 Q01650 1/20 0.39
CTSK P43235 1/20 0.38
ANPEP P15144 2/20 0.37
RNPEP Q9H4A4 2/20 0.37
DNPEP Q9ULA0 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9572314 1.00 DPP7 (0.45) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL24759754 0.90 SLC7A5 (0.41) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL8269796 0.83 SLC7A5 (0.44) DPP7DPP9DPP8DPP4SLC1A3
SCHEMBL9572303 0.83 SLC7A5 (0.47) SLC1A3SLC1A2SLC7A5ANPEPRNPEP
SCHEMBL9572304 0.80 FOLH1 (0.38) SLC7A5ANPEPRNPEPDNPEP
SCHEMBL12156779 0.80 DPP7 (0.41) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL28564205 0.79 ALDH1A1 (0.47) PLA2G10CTSK
SCHEMBL8972235 0.79 ALDH1A1 (0.47) PLA2G10CTSK
SCHEMBL4010441 0.79 PLA2G10 (0.44) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL4008872 0.79 PLA2G10 (0.44) DPP7DPP9DPP8DPP4SLC15A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5510531-A ANTIINFLAMMATROY AGENTS, MUSCULAR DISORDERS SUNTORY LIMITED (JP) 1996-04-23 US disclosed
EP-0393457-B1 Proteinase inhibitor SUNTORY LTD (JP) 1994-07-06 EP disclosed
US-5081284-A N-Oxomethyl-Substituted Peptide SUNTORY LIMITED (JP) 1992-01-14 US disclosed
EP-0393457-A1 Proteinase inhibitor SUNTORY LIMITED (JP) 1990-10-24 EP disclosed