SCHEMBL9572304

SCHEMBL9572304

CSCCC(CO)NC(=O)[C@@H](N)CC(C)C

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.38
METAP2 P50579 1/20 0.38
METAP1 P53582 1/20 0.38
SLC7A5 Q01650 1/20 0.38
ANPEP P15144 2/20 0.36
RNPEP Q9H4A4 2/20 0.36
DNPEP Q9ULA0 1/20 0.36
FNTA P49354 3/20 0.36
FNTB P49356 3/20 0.36
LARS1 Q9P2J5 1/20 0.35
SCN9A Q15858 3/20 0.34
TSHR P16473 1/20 0.34
PGGT1B P53609 1/20 0.33
CYP2C9 P11712 1/20 0.33
AAK1 Q2M2I8 1/20 0.33
CTSB P07858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24759754 0.83 SLC7A5 (0.41) SLC7A5ANPEPRNPEPDNPEPLARS1
SCHEMBL9572303 0.82 SLC7A5 (0.47) SLC7A5ANPEPRNPEPDNPEPLARS1
SCHEMBL9572314 0.80 DPP7 (0.45) SLC7A5ANPEPRNPEPDNPEP
SCHEMBL7330769 0.80 DPP7 (0.45) SLC7A5ANPEPRNPEPDNPEP
SCHEMBL8972190 0.79 ALDH1A1 (0.46) FOLH1CTSB
SCHEMBL8269796 0.79 SLC7A5 (0.44) SLC7A5ANPEPRNPEPDNPEPLARS1
SCHEMBL2545495 0.79 FOLH1 (0.55) FOLH1SLC7A5FNTAFNTBPGGT1B
SCHEMBL31372921 0.79 FOLH1 (0.55) FOLH1SLC7A5FNTAFNTBPGGT1B
SCHEMBL11141977 0.79 FOLH1 (0.55) FOLH1SLC7A5FNTAFNTBPGGT1B
SCHEMBL9561661 0.79 FOLH1 (0.55) FOLH1SLC7A5FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0543310-A2 Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same SUNTORY LIMITED (JP) 1993-05-26 EP disclosed