Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262816 | 0.81 | TDP1 (0.54) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL10140559 | 0.81 | TDP1 (0.54) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL14610894 | 0.79 | TDP1 (0.52) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL5605835 | 0.78 | CYP3A4 (0.48) | TDP1ALOX15CYP3A4ALDH1A1MAPT | |
| SCHEMBL16543023 | 0.78 | CASP1 (0.42) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL8338686 | 0.77 | TDP1 (0.50) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL12889181 | 0.77 | HPGD (0.45) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL6707715 | 0.76 | TDP1 (0.48) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL2014730 | 0.76 | LMNA (0.50) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL22592437 | 0.76 | PRKCI (0.40) | TDP1ALOX15CYP3A4SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11802136-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-31 | — | — | US | disclosed |
| WO-2023191536-A1 | THIOBENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF | 고려대학교 산학협력단 | 2023-10-05 | — | — | WO | disclosed |
| EP-4249525-A1 | METHOD FOR MANUFACTURING PERFLUOROELASTOMER AQUEOUS DISPERSION, COMPOSITION, CROSSLINKABLE COMPOSITION, AND CROSSLINKED PRODUCT | DAIKIN INDUSTRIES, LTD. (JP) | 2023-09-27 | — | — | EP | disclosed |
| EP-3573960-B1 | N-{[2-(PIPERIDIN-1-YL)PHENYL](PHENYL)METHYL}-2-(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-7-YL)ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ROR-GAMMA MODULATORS FOR TREATING AUTOIMMUNE DISEASES | GENFIT (FR) | 2023-08-16 | — | — | EP | disclosed |
| EP-4198020-A1 | ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME, AND ELECTRONIC APPARATUS | Shaanxi Lighte Optoelectronics Material Co., Ltd. (CN) | 2023-06-21 | — | — | EP | disclosed |
| WO-2023005614-A1 | FRAME STRUCTURE-BASED NANOPARTICLE USED FOR MASS CYTOMETRY AND PREPARATION METHOD THEREFOR | 浙江大学 | 2023-02-02 | — | — | WO | disclosed |
| EP-3715423-B1 | HIGH WET FAST DISPERSE DYE MIXTURES OF N-[4-(5-FLUORO-2,4-DINITRO-PHENYLAZO)-PHENYL]-AMINE DERIVATIVES AND N-[4-(4-NITRO-PHENYLAZO)-PHENYL]-AMINE DERIVATIVES | DYSTAR COLOURS DISTRIB GMBH (DE) | 2022-05-11 | — | — | EP | disclosed |
| WO-2021139775-A1 | PYRIDONE COMPOUND AND APPLICATION | 江苏先声药业有限公司 | 2021-07-15 | — | — | WO | disclosed |
| EP-3162802-B1 | 2-(3-PYRIDINYL)-1H-BENZIMIDAZOLE DERIVATIVE COMPOUND AND MEDICINE CONTAINING SAME | NIHON MEDIPHYSICS CO LTD (JP) | 2020-08-19 | — | — | EP | disclosed |
| US-20200140471-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2020-05-07 | — | — | US | disclosed |
| US-20090192169-A1 | Bicyclic Benzimidazole Compounds and Their Use as Metabotropic Glutamate Receptor Potentiators | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | US | disclosed |
| EP-1711184-B1 | (3-OXO-3,4-DIHYDRO-QUINOXALIN-2-YL-AMINO)-BENZAMIDE DERIVATIVES AND RELATED COMPOUNDS AS GLYCOGEN PHOSPHORYLASE INHIBITORS FOR THE TREATMENT OF DIABETES AND OBESITY | JANSSEN PHARMACEUTICA NV (BE) | 2007-07-18 | — | — | EP | disclosed |
| WO-2004083174-A2 | SULFONYL-AMIDINO CONTAINING AND TETRAHYDROPYRIMIDINO CONTAINING COMPOUNDS AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |
| CN-1027536-C | Process for producing 4,5,6,7-tetrahydrobenzimidazole derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1995-02-01 | — | — | CN | disclosed |
| EP-0376624-B1 | 4,5,6,7-Tetrahydrobenzimidazole derivatives and their preparation | YAMANOUCHI PHARMA CO LTD (JP) | 1994-09-14 | — | — | EP | disclosed |
| US-4977175-A | GASTROINTESTINAL DISORDERS, ANTIEMETICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-12-11 | — | — | US | disclosed |
| CN-1043706-A | 4,5,6,7-tetrahydrobenzene benzimidazole derivative preparation method | YAMANOUCHI PHARMA CO LTD (JP) | 1990-07-11 | — | — | CN | disclosed |
| EP-0376624-A1 | 4,5,6,7-Tetrahydrobenzimidazole derivatives and their preparation | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |
| US-4173631-A | ANTIPROTOZOA AGENTS, PARASITICIDES | MERCK & CO., INC. (US) | 1979-11-06 | — | — | US | disclosed |
| US-3931215-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140471-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OSBP, OCIAD1, OCIAD2 | TDP1 1645/4885ALOX15 97/4885CYP3A4 264/4885 |
| US-20090192169-A1 | Bicyclic Benzimidazole Compounds and Their Use as Metabotropic Glutamate Receptor Potentiators | GRM1, GRIN1, GRM2 | TDP1 4163/4885ALOX15 3144/4885CYP3A4 1310/4885 |
| US-11802136-B2 | Organic electroluminescent materials and devices | OSBP, OCIAD1, OCIAD2 | TDP1 1645/4885ALOX15 97/4885CYP3A4 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.