Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.41 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.41 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332741 | 0.87 | MAPK14 (0.37) | NPC1KDM4EMAPTTP53 | |
| SCHEMBL7331144 | 0.86 | PTPN11 (0.50) | RAB9AKMT2APARP10PARP2PARP15 | |
| SCHEMBL7337608 | 0.86 | RAB9A (0.43) | NPC1RAB9AKDM4EMAPTTP53 | |
| SCHEMBL7335512 | 0.79 | DCTPP1 (0.43) | NPC1RAB9AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL7330585 | 0.74 | ALDH1A1 (0.53) | NPC1RAB9AKDM4EMAPTPOLB | |
| SCHEMBL7338080 | 0.73 | DCTPP1 (0.42) | NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL7331138 | 0.71 | PARP10 (0.51) | NPC1RAB9AKMT2APARP10PARP2 | |
| SCHEMBL18747058 | 0.71 | PARP10 (0.51) | NPC1RAB9AKMT2APARP10PARP2 | |
| SCHEMBL7338395 | 0.70 | DCTPP1 (0.42) | NPC1RAB9AKMT2AKDM4EMAPT | |
| SCHEMBL7329929 | 0.70 | DCTPP1 (0.40) | NPC1RAB9AKMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191124-B1 | VIRICIDES | PHARMACIA & UPJOHN COMPANY | 2001-02-20 | — | — | US | claimed |
| EP-0757692-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-12 | — | — | EP | claimed |
| WO-1995029922-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-09 | — | — | WO | claimed |
| US-6191124-B1 | VIRICIDES | PHARMACIA & UPJOHN COMPANY | 2001-02-20 | — | — | US | disclosed |
| EP-0757692-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029922-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-09 | — | — | WO | disclosed |