Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | HTR3A | P46098 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12192898 | 0.87 | ROCK1 (0.61) | MAOAMAOBACHE | |
| SCHEMBL8549837 | 0.86 | CCR3 (0.63) | — | |
| Hydrochloric Acid SCHEMBL8681764 | 0.84 | CCR3 (0.61) | — | |
| SCHEMBL7296120 | 0.83 | ALDH1A1 (0.65) | ACHE | |
| SCHEMBL466899 | 0.82 | SIGMAR1 (0.68) | — | |
| SCHEMBL9737745 | 0.82 | SLC6A2 (0.63) | SLC6A2SLC6A4 | |
| SCHEMBL13450914 | 0.82 | MAOA (0.58) | MAOAMAOBACHE | |
| SCHEMBL14163892 | 0.81 | — | — | |
| SCHEMBL8935814 | 0.81 | MAOA (0.59) | MAOAMAOBACHE | |
| SCHEMBL16902875 | 0.81 | SLC6A2 (0.78) | SLC6A2SLC6A4HTR3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169855-A | PIPERIDINE ETHER DERIVATIVES AS PSYCHOTROPIC DRUGS OR PLANT FUNGICIDES | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0449187-A2 | Piperidin ether derivatives as psychotropic drugs or plant fungicides | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-10-02 | — | — | EP | disclosed |