Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26606605 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL1096952 | 0.74 | KDM4E (0.59) | KDM4EALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL21711920 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL12780361 | 0.73 | KMT2A (0.50) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL198937 | 0.72 | KDM4E (0.69) | KDM4EALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL522695 | 0.72 | KDM4E (0.57) | KDM4EALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL18306466 | 0.72 | HDAC1 (0.59) | KDM4EALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL4730659 | 0.72 | HSD17B10 (0.63) | KDM4EALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL18172323 | 0.71 | KDM4E (0.57) | KDM4EALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL5177009 | 0.71 | ALDH1A1 (0.61) | KDM4EALDH1A1LMNAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475531-B1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | ASAHI CHEMICAL IND (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0475531-A1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-03-18 | — | — | EP | disclosed |