Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12370455 | 0.82 | EPHX2 (0.47) | NR3C1EPHX2KMT2APOLB | |
| SCHEMBL12370450 | 0.82 | HRH3 (0.41) | NR3C1EPHX2HTR2AKMT2AMEN1 | |
| SCHEMBL87863 | 0.80 | HSD17B10 (0.59) | HSD17B10TSHRHTR2AKMT2ACYP1A2 | |
| SCHEMBL12370402 | 0.79 | EPHX2 (0.45) | NR3C1EPHX2KMT2A | |
| SCHEMBL12370458 | 0.77 | EPHX2 (0.50) | EPHX2KMT2A | |
| SCHEMBL12370382 | 0.71 | EPHX2 (0.40) | NR3C1EPHX2KMT2AALDH1A1MAPT | |
| SCHEMBL13500221 | 0.69 | RAB9A (0.58) | NR3C1KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL14062472 | 0.69 | MAOA (0.54) | HSD17B10HTR2BEPHX2KMT2AMEN1 | |
| SCHEMBL24634723 | 0.68 | LCK (0.54) | EPHX2HTR2AALDH1A1MAPT | |
| SCHEMBL15800630 | 0.68 | PTPRC (0.59) | HSD17B10KMT2AMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721210-A | OLIGOPEPTIDES AS ANTIINFLAMMATORY AGENTS OR INTEGRIN RECEPTOR ANTAGONISTS | TANABE SEIYAKU CO., LTD. (JP) | 1998-02-24 | — | — | US | disclosed |
| EP-0538399-A4 | — | — | 1994-05-04 | — | — | EP | disclosed |
| EP-0538399-A1 | CYCLIC CELL ADHESION MODULATION COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5192746-A | Cyclized integrin receptor antagonist compounds including adhesion to fibronectins, oligopeptides | TANABE SEIYAKU CO., LTD. (JP) | 1993-03-09 | — | — | US | disclosed |
| WO-1992000995-A1 | CYCLIC CELL ADHESION MODULATION COMPOUNDS | TANABE SEIYAKU CO. LTD. (JP) | 1992-01-23 | — | — | WO | disclosed |