Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328447 | 0.94 | MEN1 (0.50) | ALOX5CYP1A2CYP3A4TSHRCYP2C9 | |
| SCHEMBL7333786 | 0.90 | MEN1 (0.50) | ALOX5CYP1A2CYP3A4TSHRCYP2C9 | |
| SCHEMBL7329378 | 0.90 | HTR2A (0.59) | ALOX5CYP1A2CYP3A4TSHRCYP2C9 | |
| SCHEMBL7334714 | 0.88 | KMT2A (0.53) | ALOX5CYP1A2CYP1A1CYP1B1PTGS2 | |
| Water SCHEMBL9660219 | 0.71 | HTR2A (0.52) | HTR2AHTR2CHTR2BMAPT | |
| Water SCHEMBL9660223 | 0.71 | HTR2A (0.52) | HTR2AHTR2CHTR2BMAPT | |
| Hydrochloric Acid SCHEMBL9658330 | 0.71 | HTR2A (0.52) | HTR2AHTR2CHTR2BMAPT | |
| Hydrochloric Acid SCHEMBL9658321 | 0.71 | HTR2A (0.44) | ALOX5HTR2AHTR2CHTR2B | |
| SCHEMBL2334779 | 0.70 | HTR2A (0.55) | HTR2AHTR2CHTR2BKMT2A | |
| SCHEMBL7328556 | 0.70 | MEN1 (0.47) | CYP1A2CYP3A4TSHRCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405848-A | Substituted thiazolylaminotetrahydropyridopyrimidines derivatives useful as platelet aggregation inhibitors | ORTHO PHARMACEUTICAL CORPORATION (US) | 1995-04-11 | — | — | US | claimed |