Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 0.59 |
| ▸ | HTR2C | P28335 | 12/20 | 0.59 |
| ▸ | HTR2B | P41595 | 12/20 | 0.59 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328447 | 0.94 | MEN1 (0.50) | HTR2AHTR2CHTR2BMEN1NPC1 | |
| SCHEMBL7331115 | 0.90 | ALOX5 (0.51) | HTR2AHTR2CHTR2BMEN1NPC1 | |
| SCHEMBL7333786 | 0.90 | MEN1 (0.50) | HTR2AHTR2CHTR2BMEN1NPC1 | |
| SCHEMBL7334714 | 0.88 | KMT2A (0.53) | MEN1NPC1RAB9AKMT2ASENP8 | |
| SCHEMBL183435 | 0.75 | HTR2A (1.00) | HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL9658377 | 0.71 | HTR2A (0.61) | HTR2AHTR2CHTR2B | |
| SCHEMBL7328556 | 0.70 | MEN1 (0.47) | MEN1NPC1RAB9AKMT2ASENP8 | |
| SCHEMBL1820221 | 0.69 | NPY5R (0.88) | NPY5RMEN1NPC1RAB9AKMT2A | |
| SCHEMBL29276759 | 0.69 | NPY5R (1.00) | NPY5RMEN1NPC1RAB9AKMT2A | |
| SCHEMBL183797 | 0.69 | HTR2C (1.00) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405848-A | Substituted thiazolylaminotetrahydropyridopyrimidines derivatives useful as platelet aggregation inhibitors | ORTHO PHARMACEUTICAL CORPORATION (US) | 1995-04-11 | — | — | US | claimed |