Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RBP4 | P02753 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330529 | 0.87 | KDM4E (0.48) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL7324003 | 0.79 | KDM4E (0.50) | ALDH1A1CYP3A4CYP2C19MAPTLMNA | |
| SCHEMBL7331892 | 0.79 | TSHR (0.49) | LMNAMEN1KMT2A | |
| SCHEMBL7334780 | 0.78 | MEN1 (0.40) | ALDH1A1MAPTNPC1LMNAMEN1 | |
| SCHEMBL7334149 | 0.77 | PTGDR2 (0.44) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7325586 | 0.77 | GAA (0.53) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7335424 | 0.77 | KMT2A (0.42) | ALDH1A1MAPTNPC1LMNAMEN1 | |
| Fumaric Acid SCHEMBL7326007 | 0.74 | ALDH1A1 (0.45) | ALDH1A1CYP1A2CYP3A4CYP2C19RBP4 | |
| SCHEMBL7333021 | 0.73 | GPBAR1 (0.34) | ALDH1A1LMNAMEN1KMT2A | |
| Fumaric Acid SCHEMBL7326008 | 0.73 | ALDH1A1 (0.45) | ALDH1A1CYP1A2CYP3A4CYP2C19RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376624-B1 | 4,5,6,7-Tetrahydrobenzimidazole derivatives and their preparation | YAMANOUCHI PHARMA CO LTD (JP) | 1994-09-14 | — | — | EP | disclosed |