Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945428 | 0.89 | LMNA (0.39) | LMNASMN1; SMN2KDM4EALDH1A1TYR | |
| SCHEMBL11303274 | 0.80 | CA1 (0.50) | NPC1RAB9AKDM4EACHEALDH1A1 | |
| SCHEMBL2020487 | 0.78 | TDP1 (0.44) | NPC1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL2020485 | 0.78 | TDP1 (0.44) | NPC1RAB9ALMNASMN1; SMN2KDM4E | |
| SCHEMBL6258179 | 0.78 | CA1 (0.39) | MAOB | |
| SCHEMBL8551056 | 0.78 | SOS1 (0.35) | MAOAMAOBSOS1 | |
| SCHEMBL7752555 | 0.77 | CA4 (0.40) | LMNASMN1; SMN2TDP1 | |
| SCHEMBL2282297 | 0.77 | CA4 (0.40) | LMNASMN1; SMN2TDP1 | |
| SCHEMBL7154266 | 0.76 | SLC6A2 (0.45) | NFE2L2NPC1RAB9AACHEMAOB | |
| SCHEMBL10364397 | 0.76 | SLC6A2 (0.45) | NFE2L2NPC1RAB9AACHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076647-A2 | ANTIPSYCHOTIC INDOLYL DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055672-A2 | ANTIPSYCHOTIC INDOLYL DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-04 | — | — | WO | disclosed |
| EP-0842174-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING MYOCARDIAL ISCHAEMIA | PIERRE FABRE MEDICAMENT (FR) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005134-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING MYOCARDIAL ISCHAEMIA | PIERRE FABRE MEDICAMENT (FR) | 1997-02-13 | — | — | WO | disclosed |
| WO-1993025528-A1 | NOVEL AMINOPROPANOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1993-12-23 | — | — | WO | disclosed |