Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945428 | 0.79 | LMNA (0.39) | CA12CA9 | |
| SCHEMBL7332087 | 0.78 | NFE2L2 (0.36) | SOS1MAOBMAOA | |
| SCHEMBL10364397 | 0.76 | SLC6A2 (0.45) | SLC6A4FFAR1MAOB | |
| SCHEMBL7154266 | 0.76 | SLC6A2 (0.45) | SLC6A4FFAR1MAOB | |
| SCHEMBL10339033 | 0.75 | SLC6A2 (0.36) | SLC6A4CA12CA9MEN1GAA | |
| SCHEMBL844654 | 0.73 | CYP2A6 (0.50) | CA9MEN1GAAMAPTKMT2A | |
| SCHEMBL7918190 | 0.72 | SLC6A4 (0.45) | HTR2ASLC6A4MEN1KMT2A | |
| SCHEMBL24974304 | 0.72 | GRIN1 (0.47) | SOS1SLC6A4MAOBAOC3GRIN1 | |
| SCHEMBL11303274 | 0.71 | CA1 (0.50) | CA12CA9MEN1GAAMAPT | |
| SCHEMBL2020485 | 0.69 | TDP1 (0.44) | MAOBMAOAMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842174-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING MYOCARDIAL ISCHAEMIA | PIERRE FABRE MEDICAMENT (FR) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005134-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING MYOCARDIAL ISCHAEMIA | PIERRE FABRE MEDICAMENT (FR) | 1997-02-13 | — | — | WO | disclosed |