Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154266 | 1.00 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3NFE2L2ACHE | |
| SCHEMBL10339033 | 0.86 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3ACHE | |
| SCHEMBL31707544 | 0.79 | ACHE (0.50) | SLC6A2SLC6A4SLC6A3ACHE | |
| SCHEMBL7918190 | 0.78 | SLC6A4 (0.45) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11080783 | 0.77 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3MAOBNPC1 | |
| SCHEMBL7332087 | 0.76 | NFE2L2 (0.36) | NFE2L2ACHEMAOBNPC1RAB9A | |
| SCHEMBL2282297 | 0.76 | CA4 (0.40) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL7752555 | 0.76 | CA4 (0.40) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL8551056 | 0.76 | SOS1 (0.35) | SLC6A4MAOBFFAR1 | |
| SCHEMBL11526012 | 0.75 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210849-B1 | 2-HYDROXY-3-PHENOXYPROPYL AMINES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-08-29 | — | — | EP | disclosed |