Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337026 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2HTTLMNAASAH1ALDH1A1 | |
| SCHEMBL4769824 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2HTTLMNAASAH1ALDH1A1 | |
| SCHEMBL12020950 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2HTTLMNAASAH1ALDH1A1 | |
| SCHEMBL8914641 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2HTTLMNAASAH1ALDH1A1 | |
| SCHEMBL18626198 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2HTTLMNAASAH1ALDH1A1 | |
| SCHEMBL8604263 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2HTTLMNAASAH1ALDH1A1 | |
| SCHEMBL24873117 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2HTTLMNAASAH1ALDH1A1 | |
| SCHEMBL10585453 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2HTTLMNAASAH1ALDH1A1 | |
| SCHEMBL1577945 | 0.81 | SMN1; SMN2 (0.75) | SMN1; SMN2HTTLMNAALDH1A1 | |
| SCHEMBL3508948 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2HTTLMNAASAH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726898-B1 | PHENYLINDOLE COMPOUNDS | LUNDBECK & CO AS H (DK) | 2000-12-20 | — | — | EP | disclosed |
| US-5703087-A | PSYCHOLOGICAL DISORDERS | H. LUNDBECK A/S (DK) | 1997-12-30 | — | — | US | disclosed |
| EP-0726898-A1 | PHENYLINDOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012591-A1 | PHENYLINDOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 1995-05-11 | — | — | WO | disclosed |