Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EPOR | P19235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL553140 | 0.85 | PLAAT3 (0.50) | SMN1; SMN2LMNAHTTALDH1A1KDM4E | |
| SCHEMBL9750602 | 0.83 | ALDH1A1 (0.47) | SMN1; SMN2LMNAHTTALDH1A1KDM4E | |
| SCHEMBL8914641 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAHTTASAH1ALDH1A1 | |
| SCHEMBL7332230 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAHTTASAH1ALDH1A1 | |
| SCHEMBL488918 | 0.82 | THRB (0.53) | SMN1; SMN2LMNAHTTALDH1A1L3MBTL1 | |
| SCHEMBL13862904 | 0.80 | MEN1 (0.50) | SMN1; SMN2LMNAALDH1A1RAB9ANPC1 | |
| SCHEMBL18016179 | 0.80 | MEN1 (0.50) | SMN1; SMN2LMNAALDH1A1RAB9ANPC1 | |
| SCHEMBL316845 | 0.80 | THRB (0.54) | SMN1; SMN2LMNAHTTALDH1A1L3MBTL1 | |
| SCHEMBL7337026 | 0.80 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAHTTASAH1ALDH1A1 | |
| SCHEMBL4769824 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNAHTTASAH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140079743-A1 | COATINGS OF ACRYLAMIDE-BASED COPOLYMERS | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-20130071449-A1 | COATINGS OF ACRYLAMIDE-BASED COPOLYMERS | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2013-03-21 | — | — | US | disclosed |
| US-8333984-B2 | Coatings of acrylamide-based copolymers | ABBOTT CARDIOVASCULAR SYSTEMS, INC. (US) | 2012-12-18 | — | — | US | disclosed |
| US-20110293675-A1 | COATINGS OF ACRYLAMIDE-BASED COPOLYMERS | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-12-01 | — | — | US | disclosed |
| US-8017141-B2 | Coatings of acrylamide-based copolymers | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-09-13 | — | — | US | disclosed |
| US-20080146992-A1 | Coatings of acrylamide-based copolymers | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140079743-A1 | COATINGS OF ACRYLAMIDE-BASED COPOLYMERS | CAD, MSN, PAM | SMN1; SMN2 2585/4885LMNA 3573/4885HTT 2683/4885 |
| US-20130071449-A1 | COATINGS OF ACRYLAMIDE-BASED COPOLYMERS | CAD, MSN, PAM | SMN1; SMN2 2585/4885LMNA 3573/4885HTT 2683/4885 |
| US-20110293675-A1 | COATINGS OF ACRYLAMIDE-BASED COPOLYMERS | CAD, MSN, BMP2 | SMN1; SMN2 2708/4885LMNA 3584/4885HTT 3023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.