Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | CMA1 | P23946 | 3/20 | 0.61 |
| ▸ | HTR6 | P50406 | 9/20 | 0.59 |
| ▸ | PFKFB3 | Q16875 | 6/20 | 0.58 |
| ▸ | PFKFB4 | Q16877 | 5/20 | 0.58 |
| ▸ | HTR1A | P08908 | 4/20 | 0.56 |
| ▸ | HTR1D | P28221 | 4/20 | 0.56 |
| ▸ | HTR1B | P28222 | 4/20 | 0.56 |
| ▸ | HTR7 | P34969 | 4/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | HTR2C | P28335 | 3/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | HTR1E | P28566 | 1/20 | 0.56 |
| ▸ | HTR1F | P30939 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905740 | 0.83 | NPSR1 (0.62) | NPSR1L3MBTL1CMA1HTR6PFKFB3 | |
| SCHEMBL12204617 | 0.82 | NPSR1 (0.90) | NPSR1L3MBTL1CMA1HTR6PFKFB3 | |
| SCHEMBL4710962 | 0.80 | NPSR1 (0.63) | NPSR1L3MBTL1CMA1HTR6PFKFB3 | |
| SCHEMBL10238818 | 0.80 | NPSR1 (0.63) | NPSR1L3MBTL1CMA1HTR6PFKFB3 | |
| SCHEMBL14290789 | 0.80 | NPSR1 (0.63) | NPSR1L3MBTL1CMA1HTR6PFKFB3 | |
| SCHEMBL6716754 | 0.79 | NPSR1 (0.62) | NPSR1L3MBTL1CMA1HTR6PFKFB3 | |
| SCHEMBL6720525 | 0.79 | PFKFB3 (0.59) | NPSR1L3MBTL1CMA1HTR6PFKFB3 | |
| Hydrochloric Acid SCHEMBL9958080 | 0.79 | NPSR1 (0.62) | NPSR1L3MBTL1CMA1HTR6PFKFB3 | |
| SCHEMBL10239970 | 0.79 | HTR6 (0.63) | NPSR1L3MBTL1CMA1HTR6PFKFB3 | |
| Hydrochloric Acid SCHEMBL3157122 | 0.79 | NPSR1 (0.62) | NPSR1L3MBTL1CMA1HTR6PFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138210-B2 | Substituted indanyl sulfonamide compounds, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2012-03-20 | — | — | US | disclosed |
| US-20100069378-A1 | SUBSTITUTED INDANYL SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2010-03-18 | — | — | US | disclosed |
| EP-1884515-A1 | Substituted indanyl sulfonamide compounds, their preparation and use as medicaments | Laboratorios del Dr. Esteve S.A. (ES) | 2008-02-06 | — | — | EP | disclosed |
| US-20080027073-A1 | Substituted indanyl sulfonamide compounds, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027073-A1 | Substituted indanyl sulfonamide compounds, their preparation and use as medicaments | HTR6, HTR5A, GPR6 | NPSR1 18/4885L3MBTL1 4841/4885CMA1 1471/4885 |
| US-20100069378-A1 | SUBSTITUTED INDANYL SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | HTR6, HTR5A, GPR6 | NPSR1 13/4885L3MBTL1 4861/4885CMA1 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.