SCHEMBL25318263

SCHEMBL25318263

COC(=O)c1ccc(-c2nc3cc(C(=O)OC)ccc3[nH]2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.75
ALDH1A1 P00352 2/20 0.75
SMN1; SMN2 Q16637 2/20 0.75
NPC1 O15118 1/20 0.75
LMNA P02545 1/20 0.75
PKM P14618 1/20 0.75
HPGD P15428 1/20 0.75
NFKB1 P19838 1/20 0.75
RAB9A P51151 1/20 0.75
NFKB2 Q00653 1/20 0.75
RELA Q04206 1/20 0.75
RHEB Q15382 1/20 0.74
MMP2 P08253 1/20 0.68
MMP9 P14780 1/20 0.68
MMP8 P22894 1/20 0.68
MMP13 P45452 1/20 0.68
TNKS O95271 1/20 0.59
ATM Q13315 1/20 0.56
IDO1 P14902 1/20 0.53
SIRT2 Q8IXJ6 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29906102 1.00 KDM4E (0.75) KDM4EALDH1A1SMN1; SMN2NPC1LMNA
SCHEMBL20982713 0.94 KDM4E (0.75) KDM4EALDH1A1SMN1; SMN2NPC1LMNA
SCHEMBL14381943 0.93 KDM4E (0.70) KDM4EALDH1A1SMN1; SMN2NPC1LMNA
SCHEMBL14381945 0.92 RHEB (0.71) KDM4EALDH1A1SMN1; SMN2NPC1LMNA
SCHEMBL3222740 0.92 KDM4E (0.71) KDM4EALDH1A1SMN1; SMN2NPC1LMNA
SCHEMBL1170648 0.91 KDM4E (0.61) KDM4EALDH1A1SMN1; SMN2NPC1LMNA
SCHEMBL4245435 0.91 ATM (0.65) KDM4EALDH1A1SMN1; SMN2NPC1LMNA
SCHEMBL9130717 0.90 ALDH1A1 (0.62) KDM4EALDH1A1SMN1; SMN2NPC1LMNA
SCHEMBL3206969 0.89 SMN1; SMN2 (0.68) KDM4EALDH1A1SMN1; SMN2NPC1LMNA
SCHEMBL6178276 0.88 KDM4E (0.59) KDM4EALDH1A1SMN1; SMN2NPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559589-B2 High-temperature self-crosslinking-based flame-retardant anti-dripping copolyester, and preparation method therefor and application thereof SICHUAN UNIVERSITY (CN) 2026-02-24 US disclosed
CN-114989406-B Application of non-metal organic compound in DMT method for synthesizing polyester, DMT method functional copolyester and preparation method thereof 青岛大学 2024-01-12 CN disclosed
US-20230235116-A1 HIGH-TEMPERATURE SELF-CROSSLINKING-BASED FLAME-RETARDANT ANTI-DRIPPING COPOLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SICHUAN UNIVERSITY (CN) 2023-07-27 US disclosed
EP-4169967-A1 HIGH-TEMPERATURE SELF-CROSSLINKING-BASED FLAME-RETARDANT DROPLET-RESISTANT COPOLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Sichuan University (CN) 2023-04-26 EP disclosed
CN-113817152-B Flame-retardant anti-dripping copolyester based on high-temperature self-crosslinking and preparation method and application thereof 四川大学 2022-11-11 CN disclosed
CN-114989406-A Application of non-metallic organic compound in synthesis of polyester by DMT method, DMT method functional copolyester and preparation method thereof 青岛大学 2022-09-02 CN disclosed
CN-113817152-A Flame-retardant anti-dripping copolyester based on high-temperature self-crosslinking and preparation method and application thereof 四川大学 2021-12-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559589-B2 High-temperature self-crosslinking-based flame-retardant anti-dripping copolyester, and preparation method therefor and application thereof COL1A1, F11, COL2A1 KDM4E 255/4885ALDH1A1 269/4885SMN1; SMN2 1214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.