Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 2/20 | 0.48 |
| ▸ | F13A1 | P00488 | 1/20 | 0.48 |
| ▸ | TGM1 | P22735 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 2/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333350 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GAATSHRCYP1A2CYP3A4 | |
| SCHEMBL8393648 | 0.90 | LMNA (0.58) | ALDH1A1GAATSHRCYP1A2CYP3A4 | |
| SCHEMBL594857 | 0.89 | ALDH1A1 (0.67) | ALDH1A1GAATSHRCYP1A2CYP3A4 | |
| SCHEMBL594858 | 0.89 | ALDH1A1 (0.67) | ALDH1A1GAATSHRCYP1A2CYP3A4 | |
| SCHEMBL4654803 | 0.88 | ALDH1A1 (0.65) | ALDH1A1GAATSHRCYP1A2CYP3A4 | |
| SCHEMBL6483802 | 0.87 | ALDH1A1 (0.53) | ALDH1A1GAATSHRCYP1A2CYP3A4 | |
| SCHEMBL6483798 | 0.87 | ALDH1A1 (0.53) | ALDH1A1GAATSHRCYP1A2CYP3A4 | |
| SCHEMBL7418209 | 0.87 | TSHR (0.68) | ALDH1A1GAATSHRCYP1A2CYP3A4 | |
| SCHEMBL4654802 | 0.86 | ALDH1A1 (0.52) | ALDH1A1GAATSHRCYP1A2CYP3A4 | |
| SCHEMBL6350370 | 0.86 | ALDH1A1 (0.52) | ALDH1A1GAATSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370498-A2 | Trans-4-amino(alkyl)-1-pyridylcarbamoylcyclohexane compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |
| EP-0183271-B1 | LYSIN DERIVATIVE AND PROTEINASE INHIBITOR | Okamoto, Shosuke (JP) | 1990-05-16 | — | — | EP | disclosed |
| US-4496584-A | ANTITRYPSIN, ANTIKALLIKREIN, ANTITHROMBIN OR ANTIPLASMIN AGENT | TORII & CO. LTD. (JP) | 1985-01-29 | — | — | US | disclosed |