Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CPB1 | P15086 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | F13A1 | P00488 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | TGM1 | P22735 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403759 | 0.90 | MEN1 (0.54) | ALDH1A1GAATSHRCYP3A4CYP2C9 | |
| SCHEMBL7403761 | 0.90 | MEN1 (0.54) | ALDH1A1GAATSHRCYP3A4CYP2C9 | |
| SCHEMBL8393648 | 0.89 | LMNA (0.58) | ALDH1A1GAATSHRCYP3A4CYP2C9 | |
| SCHEMBL6483802 | 0.88 | ALDH1A1 (0.53) | ALDH1A1GAATSHRCYP3A4CYP2C9 | |
| SCHEMBL6483798 | 0.88 | ALDH1A1 (0.53) | ALDH1A1GAATSHRCYP3A4CYP2C9 | |
| SCHEMBL594857 | 0.88 | ALDH1A1 (0.67) | ALDH1A1GAATSHRCYP3A4CYP2C9 | |
| SCHEMBL594858 | 0.88 | ALDH1A1 (0.67) | ALDH1A1GAATSHRCYP3A4CYP2C9 | |
| SCHEMBL9408501 | 0.88 | ALDH1A1 (0.50) | ALDH1A1GAACPB1TSHRCYP3A4 | |
| SCHEMBL4654803 | 0.87 | ALDH1A1 (0.65) | ALDH1A1GAATSHRCYP3A4CYP2C9 | |
| SCHEMBL1129080 | 0.86 | TSHR (0.50) | ALDH1A1GAACPB1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170368185-A9 | METHOD OF PREPARING DENDRITIC DRUGS | CHAI MINGHUI (CN) | 2017-12-28 | — | — | US | disclosed |
| US-9603941-B2 | Method of preparing dendritic drugs | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES | 2017-03-28 | — | — | US | disclosed |
| US-9603941-B2 | Method of preparing dendritic drugs | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES | 2017-03-28 | — | — | US | disclosed |
| US-20160206746-A1 | METHOD OF PREPARING DENDRITIC DRUGS | CHAI MINGHUI (CN) | 2016-07-21 | — | — | US | disclosed |
| US-20160206746-A1 | METHOD OF PREPARING DENDRITIC DRUGS | CHAI MINGHUI (CN) | 2016-07-21 | — | — | US | disclosed |
| US-20070190151-A1 | Method of preparing dendritic drugs | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES | 2007-08-16 | — | — | US | disclosed |
| US-20070190151-A1 | Method of preparing dendritic drugs | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES | 2007-08-16 | — | — | US | disclosed |
| US-20050261327-A1 | 2-(Bicyclo)alkylamino-derivatives as mediatores of chronic pain and inflammation | MERCK & CO., INC. | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070190151-A1 | Method of preparing dendritic drugs | MYD88, TLR3, TLR6 | ALDH1A1 3848/4885GAA 1697/4885CPB1 4411/4885 |
| US-20050261327-A1 | 2-(Bicyclo)alkylamino-derivatives as mediatores of chronic pain and inflammation | BDKRB1, BDKRB2, LTB4R2 | ALDH1A1 2563/4885GAA 4779/4885CPB1 353/4885 |
| US-20160206746-A1 | METHOD OF PREPARING DENDRITIC DRUGS | MYD88, TLR3, TLR6 | ALDH1A1 3848/4885GAA 1697/4885CPB1 4411/4885 |
| US-20170368185-A9 | METHOD OF PREPARING DENDRITIC DRUGS | MYD88, TLR3, TLR6 | ALDH1A1 3848/4885GAA 1697/4885CPB1 4411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.