Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.77 |
| ▸ | HTR2A | P28223 | 5/20 | 0.77 |
| ▸ | ACP1 | P24666 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334897 | 0.87 | DRD2 (1.00) | DRD2HTR2AACP1ALDH1A1KMT2A | |
| SCHEMBL7335126 | 0.87 | DRD2 (0.80) | DRD2HTR2AACP1ALDH1A1KMT2A | |
| Blonanserin SCHEMBL119669 | 0.87 | DRD2 (1.00) | DRD2HTR2AACP1ALDH1A1KMT2A | |
| Blonanserin SCHEMBL29379647 | 0.87 | DRD2 (1.00) | DRD2HTR2AACP1ALDH1A1KMT2A | |
| SCHEMBL7333811 | 0.86 | DRD2 (0.79) | DRD2HTR2AALDH1A1MAPTLMNA | |
| SCHEMBL7358974 | 0.85 | DRD2 (0.77) | DRD2HTR2AALDH1A1MAPTLMNA | |
| SCHEMBL7333157 | 0.83 | DRD2 (0.93) | DRD2HTR2AALDH1A1MAPTLMNA | |
| SCHEMBL7326283 | 0.78 | DRD2 (0.84) | DRD2HTR2AALDH1A1MEN1KMT2A | |
| SCHEMBL7333664 | 0.78 | DRD2 (0.76) | DRD2HTR2AALDH1A1MAPTLMNA | |
| SCHEMBL7325078 | 0.77 | HTR2A (0.80) | DRD2HTR2AMAPTLMNAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385237-B1 | 2-(1-piperazinyl)-4-phenylcycloalkanopyridine derivatives, processes for the production thereof, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5021421-A | Psychotropic agents | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0385237-A2 | 2-(1-piperazinyl)-4-phenylcycloalkanopyridine derivatives, processes for the production thereof, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |