Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.80 |
| ▸ | HTR2A | P28223 | 5/20 | 0.80 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Blonanserin SCHEMBL28204389 | 0.90 | DRD2 (0.98) | DRD2HTR2APOLBALDH1A1KDM4E | |
| SCHEMBL7334897 | 0.89 | DRD2 (1.00) | DRD2HTR2APOLBALDH1A1KDM4E | |
| Blonanserin SCHEMBL119669 | 0.89 | DRD2 (1.00) | DRD2HTR2APOLBALDH1A1KDM4E | |
| Blonanserin SCHEMBL29379647 | 0.89 | DRD2 (1.00) | DRD2HTR2APOLBALDH1A1KDM4E | |
| SCHEMBL7333811 | 0.88 | DRD2 (0.79) | DRD2HTR2APOLBALDH1A1KDM4E | |
| Blonanserin SCHEMBL28331931 | 0.88 | DRD2 (0.98) | DRD2HTR2APOLBALDH1A1KDM4E | |
| SCHEMBL7358974 | 0.87 | DRD2 (0.77) | DRD2HTR2APOLBALDH1A1KDM4E | |
| SCHEMBL7333458 | 0.87 | DRD2 (0.77) | DRD2HTR2APOLBALDH1A1GAA | |
| SCHEMBL7333157 | 0.85 | DRD2 (0.93) | DRD2HTR2APOLBALDH1A1KDM4E | |
| SCHEMBL7326283 | 0.80 | DRD2 (0.84) | DRD2HTR2APOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385237-B1 | 2-(1-piperazinyl)-4-phenylcycloalkanopyridine derivatives, processes for the production thereof, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5021421-A | Psychotropic agents | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0385237-A2 | 2-(1-piperazinyl)-4-phenylcycloalkanopyridine derivatives, processes for the production thereof, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |