Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PEPD | P12955 | 2/20 | 0.48 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19710777 | 0.88 | POLB (0.52) | POLBFKBP1AALDH1A1LMNARAB9A | |
| SCHEMBL13662643 | 0.86 | FKBP1A (0.55) | POLBFKBP1AALDH1A1LMNARAB9A | |
| SCHEMBL4179454 | 0.86 | FKBP1A (0.55) | POLBFKBP1AALDH1A1LMNARAB9A | |
| SCHEMBL7333530 | 0.86 | POLB (0.54) | POLBFKBP1AALDH1A1LMNARAB9A | |
| SCHEMBL23135776 | 0.85 | ALDH1A1 (0.54) | POLBFKBP1AALDH1A1LMNARAB9A | |
| SCHEMBL5491765 | 0.85 | LMNA (0.54) | POLBFKBP1AALDH1A1LMNARAB9A | |
| SCHEMBL2606998 | 0.85 | ALDH1A1 (0.54) | POLBFKBP1AALDH1A1LMNARAB9A | |
| SCHEMBL8248348 | 0.85 | POLB (0.52) | POLBFKBP1AALDH1A1LMNARAB9A | |
| SCHEMBL6882664 | 0.85 | LMNA (0.54) | POLBFKBP1AALDH1A1LMNARAB9A | |
| SCHEMBL683797 | 0.85 | POLB (0.52) | POLBFKBP1AALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514667-B1 | Benzazepin derivatives as vasopressin antagonists | OTSUKA PHARMA CO LTD (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5244898-A | Vasopressin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0514667-A1 | Benzazepin derivatives as vasopressin antagonists | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-25 | — | — | EP | disclosed |