Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 11/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27574649 | 0.86 | MEN1 (0.41) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL6610171 | 0.86 | LMNA (0.45) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL11709130 | 0.81 | MAPK1 (0.34) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL6584861 | 0.79 | ERCC5 (0.39) | P2RX4P2RX1P2RX3P2RX7PTBP1 | |
| SCHEMBL9471391 | 0.78 | LMNA (0.34) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL5068751 | 0.77 | P2RX4 (0.42) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL4481010 | 0.76 | CHRM2 (0.39) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL7064721 | 0.76 | P2RX4 (0.39) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL7492324 | 0.74 | L3MBTL1 (0.34) | LMNATSHRSMN1; SMN2NPSR1KDM4E | |
| SCHEMBL3100027 | 0.73 | P2RX4 (0.54) | P2RX4LMNATSHRMAPK1SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952327-A | NEUTRAL ENDOPEPTIDASE INHIBITORS; TREATMENT OF CARDIOVASCULAR DISORDERS | SOLVAY PHARMACEUTICALS GMBH (DE) | 1999-09-14 | — | — | US | disclosed |