Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.38 |
| ▸ | WNT3A | P56704 | 6/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333680 | 0.79 | P2RX4 (0.40) | PTBP1P2RX1P2RX3SMN1; SMN2NPSR1 | |
| SCHEMBL6610171 | 0.77 | LMNA (0.45) | PTBP1P2RX1P2RX3SMN1; SMN2NPSR1 | |
| SCHEMBL11709130 | 0.74 | MAPK1 (0.34) | PTBP1P2RX1P2RX3SMN1; SMN2NPSR1 | |
| SCHEMBL9471391 | 0.70 | LMNA (0.34) | P2RX1P2RX3P2RX4 | |
| SCHEMBL4481010 | 0.69 | CHRM2 (0.39) | P2RX1P2RX3SMN1; SMN2P2RX4KMT2A | |
| SCHEMBL2979170 | 0.68 | P2RX4 (0.42) | PTBP1P2RX1P2RX3SMN1; SMN2NPSR1 | |
| SCHEMBL7492324 | 0.67 | L3MBTL1 (0.34) | SMN1; SMN2NPSR1KMT2A | |
| SCHEMBL8519455 | 0.67 | CTNNB1 (0.39) | ERCC5FEN1CTNNB1WNT3ABCHE | |
| SCHEMBL5068751 | 0.66 | P2RX4 (0.42) | PTBP1P2RX1P2RX3SMN1; SMN2NPSR1 | |
| SCHEMBL7334705 | 0.65 | LMNA (0.51) | BCHEPTBP1P2RX1P2RX3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138207-A1 | Anticancer agents; side effect reduction | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1391203-A1 | ANTITUMOR AGENTS | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2004-02-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138207-A1 | Anticancer agents; side effect reduction | MKI67, TPMT, PBRM1 | ERCC5 1557/4885FEN1 611/4885CTNNB1 1960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.