Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 6/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26979432 | 0.89 | GAA (0.38) | EPHX2ALPLSLC6A4 | |
| SCHEMBL30593420 | 0.89 | GAA (0.38) | EPHX2ALPLSLC6A4 | |
| SCHEMBL7335646 | 0.84 | BACE1 (0.39) | — | |
| SCHEMBL29843138 | 0.84 | PYCR1 (0.43) | — | |
| SCHEMBL1430163 | 0.84 | PYCR1 (0.43) | — | |
| SCHEMBL24817103 | 0.84 | HRH4 (0.39) | EPHX2HRH4SLC6A4APLNR | |
| SCHEMBL4513196 | 0.81 | GAA (0.37) | APLNR | |
| SCHEMBL29771585 | 0.80 | APLNR (0.43) | APLNR | |
| SCHEMBL1364662 | 0.80 | APLNR (0.43) | APLNR | |
| SCHEMBL20512345 | 0.79 | PYCR1 (0.36) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |
| US-5968938-A | Piperazine oxytocin receptor antagonists | MERCK & CO., INC. (US) | 1999-10-19 | — | — | US | disclosed |