Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30418245 | 0.73 | HTR7 (0.58) | PTGS2HTR7CYSLTR2CYSLTR1TLR8 | |
| SCHEMBL7334166 | 0.72 | HTR7 (0.43) | PTGS2HTR7 | |
| SCHEMBL6039974 | 0.68 | HTR7 (0.59) | PTGS2MAPTHTR7CYSLTR2CYSLTR1 | |
| SCHEMBL15912814 | 0.67 | ALOX5AP (0.38) | — | |
| SCHEMBL31546289 | 0.66 | SMN1; SMN2 (0.39) | TP53MAPT | |
| SCHEMBL16815975 | 0.66 | SMN1; SMN2 (0.39) | TP53MAPT | |
| SCHEMBL28226544 | 0.66 | PTGS2 (0.43) | PTGS2MAPTHTR7CYSLTR2CYSLTR1 | |
| SCHEMBL10559616 | 0.65 | PTGS2 (0.38) | PTGS2CYSLTR2CYSLTR1TLR8EPHX2 | |
| SCHEMBL202368 | 0.65 | PTGS2 (0.55) | PTGS2CYSLTR2CYSLTR1EPHX2 | |
| SCHEMBL199655 | 0.65 | PTGS2 (0.55) | PTGS2CYSLTR2CYSLTR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143915-A | Hypotensive agents | E. R. SQUIBB & SONS, INC. (US) | 1992-09-01 | — | — | US | disclosed |