Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | DUT | P33316 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12735701 | 0.73 | LMNA (0.42) | DUT | |
| SCHEMBL30667522 | 0.73 | TAAR1 (0.41) | DUT | |
| SCHEMBL9566221 | 0.73 | TAAR1 (0.41) | DUT | |
| SCHEMBL2414603 | 0.73 | DUT (0.39) | MAOADUT | |
| SCHEMBL28999268 | 0.73 | RAB9A (0.36) | HTR7DUT | |
| SCHEMBL13508913 | 0.72 | HTR7 (0.47) | HTR7PTGS2MAOAMAOB | |
| SCHEMBL7334171 | 0.72 | PTGS2 (0.39) | HTR7PTGS2 | |
| SCHEMBL14460773 | 0.72 | HTR7 (0.62) | HTR7PTGS2MAOAMAOB | |
| SCHEMBL2417409 | 0.71 | DUT (0.34) | DUT | |
| SCHEMBL30418245 | 0.71 | HTR7 (0.58) | HTR7PTGS2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143915-A | Hypotensive agents | E. R. SQUIBB & SONS, INC. (US) | 1992-09-01 | — | — | US | disclosed |