Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | METAP2 | P50579 | 1/20 | 0.59 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.59 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.59 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | NSD2 | O96028 | 2/20 | 0.55 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17686276 | 0.86 | HPGD (1.00) | HPGDLMNAGAAL3MBTL1KMT2A | |
| SCHEMBL5364748 | 0.85 | HPGD (0.78) | HPGDLMNAGAAL3MBTL1KMT2A | |
| SCHEMBL31680569 | 0.84 | KMT2A (0.89) | HPGDLMNAGAAL3MBTL1KMT2A | |
| SCHEMBL11901003 | 0.84 | KMT2A (0.89) | HPGDLMNAGAAL3MBTL1KMT2A | |
| SCHEMBL7749859 | 0.79 | L3MBTL1 (0.53) | HPGDLMNAGAAL3MBTL1KMT2A | |
| SCHEMBL6403159 | 0.79 | KMT2A (0.69) | HPGDLMNAGAAL3MBTL1KMT2A | |
| SCHEMBL8635709 | 0.79 | KMT2A (1.00) | HPGDLMNAGAAL3MBTL1KMT2A | |
| SCHEMBL1984940 | 0.79 | KMT2A (1.00) | HPGDLMNAGAAL3MBTL1KMT2A | |
| SCHEMBL2537984 | 0.79 | GAA (0.53) | HPGDLMNAGAAL3MBTL1ALDH1A1 | |
| SCHEMBL1979028 | 0.77 | KMT2A (0.71) | HPGDLMNAGAAL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686486-A | 4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl b!pyran-2-ones useful to treat retroviral infections | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-11 | — | — | US | claimed |
| US-5804581-A | ADMINISTERING ENZYME INHIBITOR TO TREAT OSTEOARTHRITIS, RHEUMATOID ARTHRITIS, SEPTIC ARTHRITIS, PERIODONTAL DISORDERS, CORNEAL ULCERATION, PROTEINURIA, OSTEOPENIAS, DYSTROPHY, CORONARY THROMBOSIS, TUMOR METASTASIS AND BULLOSA | BAYER CORPORATION (US) | 1998-09-08 | — | — | US | disclosed |
| US-5686486-A | 4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl b!pyran-2-ones useful to treat retroviral infections | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-11 | — | — | US | disclosed |