SCHEMBL1979028

SCHEMBL1979028

O=C(NCc1ccccc1)c1ccccc1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.71
CA1 P00915 1/20 0.69
CA9 Q16790 1/20 0.69
HPGD P15428 4/20 0.67
GAA P10253 2/20 0.67
LMNA P02545 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
NPC1 O15118 1/20 0.66
ALDH1A1 P00352 1/20 0.66
MAPT P10636 1/20 0.66
TSHR P16473 1/20 0.66
HTT P42858 1/20 0.66
NPSR1 Q6W5P4 1/20 0.66
HSD17B10 Q99714 1/20 0.66
NLRP1 Q9C000 1/20 0.66
APEX1 P27695 1/20 0.66
METAP2 P50579 1/20 0.65
CHRNB2 P17787 1/20 0.65
CHRNB4 P30926 1/20 0.65
CHRNA3 P32297 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3192733 0.89 KMT2A (0.67) KMT2ACA1CA9HPGDGAA
SCHEMBL31680569 0.88 KMT2A (0.89) KMT2AHPGDGAALMNAL3MBTL1
SCHEMBL11901003 0.88 KMT2A (0.89) KMT2AHPGDGAALMNAL3MBTL1
SCHEMBL12472363 0.86 KMT2A (0.72) KMT2ACA1CA9HPGDLMNA
SCHEMBL13812768 0.86 LIPG (0.62) KMT2ACA1CA9HPGDGAA
SCHEMBL8635709 0.83 KMT2A (1.00) KMT2AHPGDGAALMNAL3MBTL1
SCHEMBL1984940 0.83 KMT2A (1.00) KMT2AHPGDGAALMNAL3MBTL1
SCHEMBL2267873 0.83 HSP90AA1 (0.64) KMT2ACA1CA9HPGDGAA
SCHEMBL8404892 0.82 NPC1 (0.62) KMT2ACA1CA9NPC1APEX1
SCHEMBL1543219 0.82 ALDH1A1 (0.57) KMT2ACA1CA9HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115487316-B Potassium ion selective filter membrane/magnetic mesoporous nanocomposite, fluorescence/magnetic resonance dual-mode imaging probe and application 浙江大学 2024-06-07 CN claimed
CN-109876157-A Ion specificity filter membrane/mesoporous silicon composite material, nano-sensor and products thereof and application 浙江大学 2019-06-14 CN claimed
CN-101932325-A Ido inhibitors NEWLINK GENETICS 2010-12-29 CN claimed
US-20070148185-A1 Novel therapeutic target for protozoal diseases VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY 2007-06-28 US claimed
WO-2007047579-A2 A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2007-04-26 WO claimed
CN-119424687-A Brain-targeted neuron ion signal specific bimodal nanoprobe, preparation method and application 上海交通大学 2025-02-14 CN disclosed
CN-115487316-B Potassium ion selective filter membrane/magnetic mesoporous nanocomposite, fluorescence/magnetic resonance dual-mode imaging probe and application 浙江大学 2024-06-07 CN disclosed
US-20230140290-A1 SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING THE BOARD OF REGENTS OF THE UNIV OF TEXAS SY (US) 2023-05-04 US disclosed
CN-115487316-A Potassium ion selective filter membrane/magnetic mesoporous nanocomposite material, fluorescence/magnetic resonance bimodal imaging probe and application 浙江大学 2022-12-20 CN disclosed
EP-4093401-A1 SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING The Board of Regents of the University of Texas System (US) 2022-11-30 EP disclosed
US-11421049-B2 Photopolymerization synergist Piedmont Chemical Industries, LLC (US) 2022-08-23 US disclosed
WO-2021151104-A1 SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-07-29 WO disclosed
EP-2018166-A2 TEREPHTHALAMATE COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS HIV INTEGRASE INHIBITORS IRM LLC (BM) 2009-01-28 EP disclosed
WO-2008073138-A2 TEREPHTHALAMATE COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS HIV INTEGRASE INHIBITORS IRM LLC (BM) 2008-06-19 WO disclosed
WO-2008073138-A2 TEREPHTHALAMATE COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS HIV INTEGRASE INHIBITORS IRM LLC (BM) 2008-06-19 WO disclosed
EP-1809332-A2 COMPOSITIONS FOR MULTI-STEP DELIVERY OF HOT-SPOTS RADIATION TO CANCER CELLS Oncologic, Inc. (US) 2007-07-25 EP disclosed
US-20070148185-A1 Novel therapeutic target for protozoal diseases VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY 2007-06-28 US disclosed
US-20060018908-A1 Compositions and methods for treating cancer ROSE, DAVID STUART 2006-01-26 US disclosed
WO-2006010165-A2 COMPOSITIONS FOR MULTI-STEP DELIVERY OF HOT-SPOTS RADIATION TO CANCER CELLS ONCOLOGIC, INC. (US) 2006-01-26 WO disclosed
US-20050058652-A1 Method and composition for the treatment of cancer by the enzymatic conversion of soluble radioactive toxic precipitates in the cancer ROSE, DAVID STUART 2005-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230140290-A1 SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING EIF2AK2, SARS1, ACE KMT2A 1142/4885CA1 2072/4885CA9 1601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.