Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334386 | 1.00 | PLAU (0.44) | PLAURELAMEN1ALDH1A1KMT2A | |
| SCHEMBL7343141 | 0.85 | PLAU (0.59) | PLAURELAMEN1ALDH1A1KMT2A | |
| SCHEMBL7336089 | 0.85 | PLAU (0.59) | PLAURELAMEN1ALDH1A1KMT2A | |
| SCHEMBL13484115 | 0.83 | CYP1A2 (0.50) | RELAMAOBCYP1A2CYP2A6NQO2 | |
| SCHEMBL7337316 | 0.80 | PLAU (0.72) | PLAU | |
| SCHEMBL7337309 | 0.80 | PLAU (0.72) | PLAU | |
| SCHEMBL7335620 | 0.79 | KDM4E (0.53) | PLAUMEN1ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL7345665 | 0.78 | RELA (0.49) | RELAALDH1A1MAOBCYP1A2CYP2A6 | |
| SCHEMBL14198012 | 0.75 | CHRM5 (0.58) | RELAMEN1ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL8845678 | 0.70 | MAPT (0.55) | PLAURELAMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |