Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336163 | 0.85 | REN (0.89) | REN | |
| SCHEMBL7332395 | 0.85 | REN (0.77) | REN | |
| SCHEMBL10420912 | 0.82 | REN (0.58) | REN | |
| SCHEMBL7330067 | 0.80 | REN (1.00) | REN | |
| SCHEMBL7297553 | 0.77 | REN (0.53) | REN | |
| SCHEMBL7305156 | 0.77 | REN (0.65) | REN | |
| SCHEMBL7382898 | 0.76 | REN (0.39) | REN | |
| SCHEMBL8909404 | 0.76 | REN (0.62) | REN | |
| SCHEMBL7303652 | 0.75 | REN (0.57) | REN | |
| SCHEMBL7271925 | 0.75 | REN (0.57) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023338-A | Renin inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-11 | — | — | US | claimed |
| US-5095119-A | Renin inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-03-10 | — | — | US | disclosed |
| US-5075451-A | Pyrrolimidazolones useful as renin inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-24 | — | — | US | disclosed |
| US-5064965-A | Renin inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |
| US-5023338-A | Renin inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-11 | — | — | US | disclosed |