Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342164 | 0.73 | LMNA (0.37) | LMNAMAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7733701 | 0.69 | L3MBTL1 (1.00) | L3MBTL1LMNAPOLBMAPTALDH1A1 | |
| SCHEMBL3736169 | 0.68 | L3MBTL1 (0.73) | L3MBTL1LMNAMAPTALDH1A1HTT | |
| SCHEMBL12788587 | 0.68 | L3MBTL1 (0.73) | L3MBTL1LMNAMAPTALDH1A1CA12 | |
| SCHEMBL7334393 | 0.68 | AR (0.42) | L3MBTL1MAPTAR | |
| SCHEMBL12156644 | 0.67 | L3MBTL1 (0.70) | L3MBTL1LMNAPOLBMAPTALDH1A1 | |
| SCHEMBL2581334 | 0.67 | L3MBTL1 (0.70) | L3MBTL1LMNAPOLBMAPTALDH1A1 | |
| SCHEMBL3022084 | 0.66 | EPHX2 (0.71) | L3MBTL1LMNAMAPTALDH1A1 | |
| SCHEMBL14256552 | 0.65 | L3MBTL1 (0.73) | L3MBTL1LMNAMAPTALDH1A1HTT | |
| SCHEMBL28405760 | 0.65 | L3MBTL1 (0.66) | L3MBTL1LMNAMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968938-A | Piperazine oxytocin receptor antagonists | MERCK & CO., INC. (US) | 1999-10-19 | — | — | US | disclosed |