Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.39 |
| ▸ | UGCG | Q16739 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339466 | 0.77 | RXRA (0.36) | CYP2C9CYP1A2UGCG | |
| SCHEMBL7342162 | 0.73 | MEN1 (0.39) | ARL3MBTL1UGCGMAPT | |
| SCHEMBL429691 | 0.72 | CYP3A4 (0.49) | L3MBTL1LCKCTSLPTPRCPTPN2 | |
| SCHEMBL7343829 | 0.70 | NR1H4 (0.47) | MAPT | |
| SCHEMBL7341428 | 0.69 | ALDH1A1 (0.41) | CYP2C9CYP2C19CYP1A2MAPT | |
| SCHEMBL1817634 | 0.68 | CA12 (0.43) | ARL3MBTL1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL7334398 | 0.68 | L3MBTL1 (0.47) | ARL3MBTL1MAPT | |
| SCHEMBL9430893 | 0.67 | AR (0.63) | ARCYP2C19 | |
| SCHEMBL2956472 | 0.66 | AR (0.44) | ARL3MBTL1 | |
| SCHEMBL5404961 | 0.65 | CYP2C9 (0.60) | ARL3MBTL1CYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |
| US-5968938-A | Piperazine oxytocin receptor antagonists | MERCK & CO., INC. (US) | 1999-10-19 | — | — | US | disclosed |