Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SPTLC2 | O15270 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445082 | 0.92 | TAS1R3 (0.43) | GRM4ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL8631788 | 0.90 | AVPR2 (0.53) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL4682920 | 0.88 | HSD17B10 (0.43) | GRM4ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL4685757 | 0.86 | MAPT (0.42) | GRM4ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL4685312 | 0.85 | AVPR2 (0.53) | ALDH1A1MAPTSMN1; SMN2USP2HSD17B10 | |
| SCHEMBL4684908 | 0.84 | GRM4 (0.40) | GRM4ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL4741540 | 0.83 | CHRM1 (0.42) | GRM4ALDH1A1KDM4EKMT2ARAB9A | |
| SCHEMBL4684434 | 0.79 | AVPR2 (0.52) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL7334873 | 0.76 | AVPR2 (0.54) | GRM4ALDH1A1KDM4EKMT2ASPTLC2 | |
| SCHEMBL4688309 | 0.76 | AVPR2 (0.41) | GRM4ALDH1A1KDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514667-B1 | Benzazepin derivatives as vasopressin antagonists | OTSUKA PHARMA CO LTD (JP) | 1995-08-09 | — | — | EP | disclosed |
| EP-0514667-A1 | Benzazepin derivatives as vasopressin antagonists | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-25 | — | — | EP | disclosed |