Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPY2R | P49146 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682920 | 0.89 | HSD17B10 (0.43) | MAPTNPY2RRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL4741540 | 0.87 | CHRM1 (0.42) | LMNARAB9AKMT2AALDH1A1HSD17B10 | |
| SCHEMBL7334875 | 0.86 | GRM4 (0.45) | MAPTRAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4684908 | 0.78 | GRM4 (0.40) | MAPTRAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9445082 | 0.78 | TAS1R3 (0.43) | MAPTRAB9AKMT2AALDH1A1ALOX15 | |
| SCHEMBL4685751 | 0.78 | AVPR2 (0.51) | MAPTLMNAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8631788 | 0.76 | AVPR2 (0.53) | CHRM5CHRM1CHRM3HTR1AHTR2C | |
| SCHEMBL8900831 | 0.73 | CHRM1 (0.42) | MAPTNPY2RRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL4684933 | 0.72 | AVPR2 (0.51) | NPY2RKMT2ACHRM5CHRM1CHRM3 | |
| SCHEMBL4681775 | 0.72 | AVPR2 (0.57) | KMT2AALDH1A1CHRM1HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |