Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682920 | 0.92 | HSD17B10 (0.43) | CHRM1CHRM5CHRM3HSD17B10AVPR2 | |
| SCHEMBL4685757 | 0.87 | MAPT (0.42) | CHRM1CHRM5CHRM3HSD17B10LMNA | |
| SCHEMBL7334875 | 0.83 | GRM4 (0.45) | CHRM1HSD17B10AVPR2AVPR1AABCB11 | |
| SCHEMBL4697111 | 0.80 | AVPR2 (0.48) | CHRM1CHRM5CHRM3HSD17B10AVPR2 | |
| SCHEMBL9445082 | 0.79 | TAS1R3 (0.43) | CHRM1CHRM5CHRM3TP53AVPR2 | |
| SCHEMBL4684908 | 0.77 | GRM4 (0.40) | CHRM1CHRM5CHRM3HSD17B10AVPR2 | |
| SCHEMBL8628426 | 0.75 | LMNA (0.44) | CHRM1CHRM5CHRM3HSD17B10LMNA | |
| SCHEMBL8631788 | 0.74 | AVPR2 (0.53) | CHRM1CHRM5CHRM3TP53AVPR2 | |
| SCHEMBL4681166 | 0.74 | AVPR2 (0.51) | CHRM1CHRM5CHRM3LMNATP53 | |
| SCHEMBL8630617 | 0.73 | CHRM1 (0.40) | CHRM1CHRM5CHRM3LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |