Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204703 | 0.88 | L3MBTL1 (0.54) | L3MBTL1GLAHCRTR1GAAKDM4E | |
| SCHEMBL9424144 | 0.83 | L3MBTL1 (0.61) | L3MBTL1GLAHCRTR1GAAKDM4E | |
| SCHEMBL29770500 | 0.82 | KMT2A (0.58) | KDM4EKMT2ANPSR1ALDH1A1LMNA | |
| SCHEMBL628822 | 0.82 | KMT2A (0.58) | KDM4EKMT2ANPSR1ALDH1A1LMNA | |
| SCHEMBL17997506 | 0.82 | MAPK1 (0.56) | L3MBTL1KDM4EMAPTNPSR1TSHR | |
| SCHEMBL14278560 | 0.81 | ALDH1A1 (0.44) | L3MBTL1KMT2AMAPTNPSR1TSHR | |
| SCHEMBL628126 | 0.78 | KMT2A (0.53) | GAAKDM4EKMT2AMAPTTSHR | |
| SCHEMBL29315365 | 0.77 | L3MBTL1 (0.58) | L3MBTL1GLAHCRTR1GAAKDM4E | |
| SCHEMBL13430563 | 0.77 | MTNR1A (0.41) | L3MBTL1KDM4EKMT2AMAPTALDH1A1 | |
| SCHEMBL13430584 | 0.77 | KMT2A (0.47) | KDM4EKMT2ANPSR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526708-B1 | Sulfonamide, preparation and use thereof as medicine and intermediate | HOFFMANN LA ROCHE (CH) | 2000-10-18 | — | — | EP | disclosed |
| EP-0526708-A1 | Sulfonamide, preparation and use thereof as medicine and intermediate | F. HOFFMANN-LA ROCHE AG (CH) | 1993-02-10 | — | — | EP | disclosed |