Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP14 | P50281 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277428 | 0.76 | CTSK (0.37) | MMP2MMP1MMP3SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL7284520 | 0.75 | CTSK (0.36) | MMP2MMP1MMP3SMN1; SMN2KMT2A | |
| Bromide SCHEMBL10716005 | 0.75 | CTSK (0.36) | MMP2MMP1MMP3SMN1; SMN2KMT2A | |
| SCHEMBL28064653 | 0.68 | SMN1; SMN2 (0.46) | MMP2MMP1MMP9MMP14MMP3 | |
| SCHEMBL10421627 | 0.68 | KMT2A (0.42) | MMP2SMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL16732157 | 0.68 | SMN1; SMN2 (0.43) | MMP2MMP1MMP9MMP14MMP3 | |
| SCHEMBL24724891 | 0.66 | DPP4 (0.47) | MMP2TP53ALDH1A1NPSR1EPHX1 | |
| SCHEMBL4570295 | 0.66 | DPP4 (0.47) | MMP2TP53ALDH1A1NPSR1EPHX1 | |
| SCHEMBL22143669 | 0.66 | DPP4 (0.47) | MMP2TP53ALDH1A1NPSR1EPHX1 | |
| SCHEMBL10780605 | 0.66 | EPHX1 (0.37) | SMN1; SMN2TP53ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | disclosed |